Ethics of Biobanks

Ethics of Biobanks Biobank is a large collection of biological information and tissue samples kept for research purposes. It is also a powerful tool used in the study of diseases. It is an important resource in supporting different types of contemporary research such as personalised drug and genomics. Biobank enable scientist to have cross purpose research studies in which data derived from samples in biobanks can be used for multiple researches. E.g. Biobanks can enable scientist identify disease biomarkers by using large collections of samples which represent hundreds of thousands of people. Its been shown that before biobanks was invented little or known was known about different disease and biomarkers and scientist struggled to find enough samples to know what sort of disease they are dealing with. Although its not all good news for the use of Biobanks due to research ethics and medical ethics. This issues were raised because of PRIVACY whereby operating biobanks without the knowledge of governing bodies and policies could be bad for the societies that take part in Biobank programs There are types of biobanks, Tissue banks and Virtual biobanks and population banks, before I explain the types Im going to explain a lot more about biobanks Biobanks incorporate cryogenic storage facilities for samples in which it can be an individual refrigerator or a big warehouse refrigerator. They are kept up to standard by the hospital, pharmaceutical companies and universities etc. Disease oriented biobanks may be classed by design and purpose because this biobanks collect information or samples representing different forms of diseases in which it can be used to also find a biomarker associated with a specific disease. Population based biobanks are big biobanks that collect large samples from large numbers of people in a community. This is done to look for biomarkers for disease in a general population. Tissue Banks- Store and harvest human tissue for transplantation, stem cell and researches based on tissue and cells Virtual biobanks samples are collected and termed to meet national regulations and integrate epidemiological cohorts Population banks they store organic material associated with clinical, lifestyle and environmental data. Biobank ethics There are many roles which comes into effect when researchers wants to collect a human specimen for research and storing it. The issues that comes into effect are the right of the participants to be private, ownership of the specimen and where the data is derived from. Also how far the donor can consent to the research study should be considered and to which extent the donor can far in sharing research results. The main issue is that biobanks collect sample and data for different future research and it is not easy to get a specific consent for any single research. Biobank controversies[1] issue consensus controversy notes Commercialization Different aspects of biobanks serve public, private, commercial, and non-commercial interests. How can policymakers set guidelines to fairly balance public, private, commercial, and non-commercial interests? Who owns biological specimens and data derived therefrom? When biobanks and related projects are publicly funded, the result will benefit private industry. To what extent is this outcome satisfactory? (Social Fairness). It may also undermine public trust in biobanks projects. It may skew research agenda in favour of research projects which are more profitable and compromise necessary but not profitable research. discrimination, including Genetic discrimination Biobanks should prevent donor communities from facing discrimination as a result of participating in a Biobank project Research reveals private information and release of it may cause participants to face discrimination. What responsibility does the Biobank have to mitigate the problem? Participants may reveal their own information because of participation in a Biobank and subsequently face discrimination. What responsibility does the Biobank have to mitigate the problem? informed consent Donors to biobanks need a consent process adjusted specifically to biobanks. What breadth of consent should biobanks have? [2] Institutional review board It would be nice to have a robust governance system before biobanks are created. How will a good governance system be designed? The oversight institution reviewing biobanks should be independent of the Biobank. Where should checks and balances be? An individual organization needs multinational support to do international research. Who should govern when research spans different countries with different legal and personal rights standards? Privacy for research participants Donors should have their specimens sufficiently anonymised. A specimen by nature includes some data about donors how much anonym zing is sufficient? [3][4] Donors have some right to return of results. How does one return results to anonymised donors? [3][5] Donors have a right to withdraw from research. Specimens can be destroyed, but to what extent should anonymised data which has already been shared be withdrawn? [5] Data derived from specimens should be shared. Who gets access and how much? [3] Changing technology makes it difficult for researchers to say how safe participant information is. What protections can be promised? [6] Return of results Donors have a right to know the purpose of a Biobank and what results it generates When should all donors share general information and when does each donor have a personal right to personal information? Public consultation Everyone wants the researchers and community to work together. What resources should be spent doing outreach, and how much involvement does the community want, and what role should the community have? Communities should participate in writing laws, standards, and policies for research. How can communities be encouraged to participate, who represents the community, and how much involvement should there be? Patients should be involved when there is research on diseases. When people are desperate because of a disease, to what extent can they participate fairly without feeling obligation to support research? Communities which donate specimens to a Biobank should have special involvement in their Biobank. What kind of involvement? Resource sharing Research efficiency increases greatly when resources are shared. How should beneficiaries share costs? This is especially problematic when a Biobank is a national resource and another country wants access to it. Results of studies should go to the widest possible audience. When should this happen and in what way? Can results be released with commercial licensing for use?

A Million Little Pieces Character List

A Million Little Pieces Characters James (1:1) Main character, miserable, self centered, drug addict Mom (1:2) James mother, she’s always upset, sad, she cries a lot Dad (1: 2) Is in charge of most family affairs, happy, concerned Nurse (1:8) she wears all white, smiles a lot administers the shots Men in White (1:11) the men in white take him away Doctor Baker (1:15) kind eyes, rehab doctor, helpful James’s love interest Lilly (1:18) black hair and blue eyes, drug addictLilly’s Dad (1:23) Left Lilly’s family when she was four Lilly’s Mom (1:23) Heroin addict, prostitute Lilly’s Grandmother (1:23) pays for Lilly’s, cared for Lilly as a child, dies while Lilly is still in rehab Roy (1:23) James roommate, follows the rules Larry (1:25)35 southern accent, short, alcoholic Warren (1:25)50, tall, thin, well dressed John (1:26) nervous and hypersexual ninja, addicted to cokeKen (1:28) Unit recovery counselor, nice at first but ends up being a wful Hank (1:35) the driver who works at the rehab, James friend, messy looking old man with white hair and blue eyes Dentist Stevens (1:36) does James surgery, he doesn’t use pain killers Amy (1:43) James sober friend Lucinda (1:43) James sober friend Courtney (1:43) James sober friend Lincoln (1:53) Unit supervisor, he hates James Joanne (1:53) Staff psychologist, secretly dating hank Ed (1:56) short man, nosey, blue collar worker Ted (1:76) tall man, deep southern accent Bill (1:77) the founder of AAMichelle (1:80) one of the only people who comes to visit James in rehab, James’ sober friend Bald Man (1:85) Alcoholic, has a wife and two kids, cries during a group meeting and gets made fun of Mickey (2:121) the gangster that Leo looked up to as a child, adopted him when he was a teenager, married to Geena Geena (2:121) Mickey’s wife and Leonard’s adopted mother, very sweet Eric (2:125) Roy’s friend who tells the counselors that Roy picked the fig ht Julie (2:126) James friend who comes to see him in rehab, very for giving Kirk (2:126) James friend, who comes to visit him in rehab, Matt (2:161) Featherweight Champion, addicted to crackDaniel (3:247) Counselor at family rehab center Sophie (3:259) Addict, alcoholic, married to Tony, is in the same rehab as James Michael (4:353) James friend, one of the guys who go with James to the bar for his first time when he’s out of rehab Kevin (4:424) James friend, one of the guys who goes with James to the bar for his first time when he’s out of rehab Bob (4:424)James friend, one of the guys who goes with James to the bar for his first time when he’s out of rehab Chapter One- (112 pages) James is a drug addict who is angry, sad and on the verge of death.In order to stay alive he must learn to live a sober life so his family sends him to rehab. In the rehab facility he finds a group of patients he fits in with and gets in a fight with Roy. Chapter Two- (113pages) Jam es continues rehab and is doing well. He starts to make friends with Leonard and they help each other through rehab. James also begins to meet secretly with a girl named Lilly even though it’s against regulations. James has an older brother that starts coming to see him on visiting days.Chapter Three- (113 pages) James begins family counseling and is having a lot of trouble dealing with his parents. Meanwhile, Lilies grandmother gets sick so Lilly leaves the rehab facility and relapses. Despite the consequences James goes after her, he does not relapse and they return together. Chapter Four- (69 pages) Aside from having nightmares about using drugs James is doing well in rehab and Lilly is recovering. James is released from rehab, shortly after Lilly’s grandmother dies and Lilly commits suicide. James is doing well and has yet to relapse.

Introducing Ssu Scholarship Essay Samples

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cars Essay - 1928 Words

History of Cars By Kenny Carroll Motor car, road vehicle which first appeared in the 19th Century. The steam propelled the first cars, but such vehicles were not a success and the age of the motor car really dates from the introduction of the petrol-driven horseless carriages of Gottfrield Daimler and Karl Benz (1885-86). The internal combustion engine for these cars had been developed earlier by several engineers, most notably by the German, Nickolaus Otto, in 1876. The main components of a motor car, from then till now, are a body or chassis to which are attached all other parts - including the engine or power plant, the transmission system for transferring the drive to the wheels, and the steering, braking and suspension mechanisms for†¦show more content†¦Daimler licensed the French firm of Panhard and Levassor to build his engine. Levassor placed it at the front of his crude car and it drove the rear road-wheels through a clutch and a gearbox. Thus in 1891 the first car to use modern engineering layout was seen. Within three years of the appearance of the first Panhard France was staging motor races on public road. At the turn of the century, petrol, steam and electric power shared almost equal popularity for powering cars. Steam was well tried and reliable and electric vehicles held the land speed record. France had several established motor manufacturers - Panhard, Peugeot, Renault, Daracq, Delahaye and others; in Germany Benz had made the worlds first standard production car, the Velo (1894), and the Daimler company was just about to present the Mercedes to the public (1901). In the United States (USA) the automobile would develop along different lines. There the car was seen not as a rich mans toy, but as a new method of communication in a continent in which travel had been restricted by a lack of roads and great distances. Great Britain (UK), slow to start, had legislated for the car in 1896 when the road speed limits were raised and soon such companies as Lanchester, Daimler (of Coventry), Wolseley and Napier were producing cars. Encouraged by the keen interest shown by King Edward VII, motoring in Britain became an accepted method of travel - for the rich. Some British manufacturers began to contest FrenchShow MoreRelatedThe Driving Of Car Cars911 Words   |  4 Pagesgrown into a young adult cars are something I eat, breath, and dream about cars. As I got older, I constantly am modifying and making sure my car is always clean as glass. I enjoy being around cars, there is always the jeopardies of being a car enthusiast are always being annoyingly cautious of cars, having constant money issues, and also getting into trouble. First, one problem that is facing most car guys is that they are on top of the actions that happen near their car. 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